Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Polyethylene glycol 12-hydroxystearate (Solutol HS-15) 是一种通透性增强剂,是一种 Macrogol 15 羟基硬脂酸酯。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
10 g | ¥ 395 | 现货 | ||
50 g | ¥ 662 | 待询 |
产品描述 | Polyethylene glycol 12-hydroxystearate (Solutol HS-15) is a permeability enhancer. |
体外活性 | Solutol HS-15 promotes the apical-to-basolateral translocation of a model protein (insulin) across Calu-3 monolayers when applied at 37°C. Furthermore there is no statistically significant increase in insulin permeability in the presence of Solutol HS-15, relative to the respective control, at 4°C. Solutol HS-15 treated cells show a statistically significant increase in permeability towards lower molecular weight permeants (5 to 22 kDa) and an absence of a statistically significant increase in permeability of proteins with larger molecular weight, namely albumin and IgG (P>0.05 relative to control). |
别名 | Solutol HS-15 |
分子量 | 344.536 |
分子式 | C20H40O4 |
CAS No. | 61909-81-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 100 mg/mL, Sonication is recommended.
H2O: 25 mg/mL, Sonication is recommended.
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Polyethylene glycol 12-hydroxystearate 61909-81-7 Others Inhibitor inhibit Solutol Polyethylene glycol 12 hydroxystearate Solutol HS-15 Polyethylene glycol 12hydroxystearate HS-15 inhibitor